It's been mentioned before as a possibility - asking people to list expected activity levels. I agree that there's advantages and disadvantages. Could be kinda cool if we all had little gamer cards with things like timezone, pronouns, activity level, activity during the week, etc., though it makes roster creation more of a pain. Still, might be useful. Might also be interesting to, once per season, run one game with a more competitive or cutthroat focus, with adjusted rules. I know there's been some discussion of the differences between competitive and laid back players.
Flush vs Zipped above to me is a great example of potential issues beyond 72/48, I think. With the no-weekends model, you miss people like Flush, who are more likely to be active on the weekends, and while I know Zipped spoke in favor of a 48/24, sometimes that phase is gonna be fully on the weekend, something the 72-hour day avoids with at least one RL day falling during the week. Gamerunners and sign-ups have to be very clear about what's going on if we're gonna experiment more, I think. This may be even more on players; gamerunners can put it in the info, but we as players need to take a second before signing up to a given game and ask ourselves if we can meet whatever that game's standard is. At least since I've been here, there hasn't been a ton of that, outside of a few people who have some interpersonal tension over play styles or whatever and who prefer not to be in games together.